2022 Acura MDX vs 2021 Lexus GX 460 comparison

2022 Acura MDX vs. 2021 Lexus GX 460

$46,900 MSRP*

Starting Price

$53,250 MSRP

Available Trim Levels

71.4 cubic feet

Cargo Capacity

64.7 cubic feet
3.5L V6 engine


4.6L V8 engine
19 mpg city / 26 mpg hwy**

EPA-Estimated MPG

15 mpg city / 19 mpg hwy
10-speed automatic transmission


6-speed automatic transmission

If you’re shopping for a new luxury crossover to enhance your Union County commute, then the 2022 Acura MDX or 2021 Lexus GX 460 might already be at the top of your list. Only one can offer a well-balanced performance and trusted features at a price you’ll appreciate. Determine which suits you best with our breakdown of the Acura MDX vs. Lexus GX 450, then explore our inventory of luxury crossovers and SUVs to find your next ride at Springfield Acura!

Acura MDX vs. Lexus GX: Pricing and Configurations

While you may be shopping for a luxury crossover, you can still stay within your budget when you opt for the Acura MDX FWD, which has a starting price of $46,900 MSRP.* Those who choose the Lexus GX 460 might have to stretch their wallet a bit more to meet its $53,250 MSRP. The MDX lineup also offers one more trim package to pick from with the Standard, Technology, A-Spec®, Advance Packages, while the GX lineup only has three configurations to choose from.

Acura MDX vs. Lexus GX: Interior Dimensions

Many Bridgewater drivers want plenty of cabin space when they upgrade to a luxury crossover. Both the MDX and GX offer customers six or seven-passenger configurations, however, the MDX once again tops its competitor with more storage space. When you fold down the second and rear seats in each crossover, you can fit more inside the MDX, while you might have to make an extra trip to transport everything with the Lexus GX. See the cargo dimensions for these two models below:

2022 Acura MDX:

  • 71.4 cubic feet of cargo space behind the first row
  • 39.1 cubic feet of cargo space behind the second row
  • 16.3 cubic feet of cargo space behind the third row

2021 Lexus GX:

  • 64.7 cubic feet of cargo space behind the first row
  • 46.7 cubic feet of cargo space behind the second row
  • 11.6 cubic feet of cargo space behind the third row

Acura MDX vs. Lexus GX: Performance Features

The Acura MDX and Lexus GX 460 offer their own distinct performances on Staten Island roads. Despite the fact that the GX comes with a slightly larger engine, the MDX pairs its configuration with a more versatile transmission for better control, and you’ll also enjoy a stronger fuel economy. Plus, the MDX lineup offers you the chance to upgrade your standard drivetrain to the brand’s trusted Super-Handling All-Wheel-Drive system, which is not available on the GX 460. See the specs for the Acura MDX vs. Lexus GX 460 below:

2022 Acura MDX FWD:

  • 3.5L V6 engine
  • 10-speed automatic transmission
  • 19 mpg city / 26 mpg hwy** rating

2021 Lexus GX 460 4WD:

  • 4.6L V8 engine
  • 15 mpg city / 19 mpg hwy
  • 6-speed automatic transmission

Bring Home a New Acura MDX for Sale at Springfield Acura

Now that you’ve seen how the new Acura MDX vs. Lexus GX 460 compared on paper, put these luxury crossovers to the test on Union County roads. Bring home a new Acura MDX for sale from Springfield Acura, and be sure to take a look at our new vehicle specials to save on your next Acura crossover. Get a closer look the new MDX lineup with a breakdown of specific models like the Acura MDX Technology Package. Speak with a member of our finance team who can answer your questions and get the car-buying or leasing process started. Contact us today for more information on the Acura MDX vs. Lexus GX, and visit our Springfield Township dealership for a test drive! You can also see how this Acura crossover compares to other Lexus models with our breakdown of the 2022 Acura MDX vs. Lexus RX.

*Prices shown are Acura suggested retail prices only and do not include taxes, license or destination and handling charge. Destination & Handling charge for sedans (excluding PMC Edition) and SUVs (excluding PMC Edition) is $1,025.00. Destination & Handling charge for PMC Edition models and NSX is $1,995.00. Acura vehicle accessory costs, labor and installation vary. Dealers set their own prices. Please consult your selected dealer.

**Based on 2022 EPA mileage ratings. Use for comparison purposes only. Your actual mileage will vary, depending on how you drive and maintain your vehicle, driving conditions, battery pack age/condition (hybrid only) and other factors.

Springfield Acura 40.6842981, -74.3234447.